The MTHFR of All Genes?

Hi all,

I hope you’re fit and well. 

In today’s article we’re going discuss genetics, a specific gene actually. This gene plays a pivotal role in our everyday lives, or should do.

In some (me) this important sometimes lifesaving gene has been switched off. Leaving those individuals open to attack from well, the types of diseases that we see decimating society today.  

Plenty of questions arise from this genetic situation that I will attempt to explain and answer, or at least make you aware of, so you can start asking your own questions;  

  • What is the MTHFR gene and what is it’s purpose?
  • Why has this essential gene ‘just gone off’ like turning out a light?  
  • Have any of you ever heard of EPIGENTICS?  
  • What could be causing this and other genes to mutate or turn off? 
  • Who could benefit from this genetic switch off? 

Genetic Links

I’m going to cover the next 3 topics very briefly, to show where modern genetic research’s own DNA was established. This is by no means a deep dive into this subject at all.

The Theory of Evolution 

When Sir Charles Darwin’s (below right pic) book ‘On the Origin of Species’ was published in 1859, the world changed its view on where we all came from, more or less overnight. (9) The theory, often described as ‘survival of the fittest’ was known as ‘evolution by natural selection’. 

Not bad because to say it was only a theory. Which is only an idea! 


Sir Francis Gault (below left pic), Darwin’s cousin took this natural selection idea by the horns. He was the first to coin the term ‘eugenics’ and he gave birth to eugenics, the word means ‘well born’.  

Gault advocated that people who rise to the top were meant to be at the top. After all the strongest survive regardless of how they did it.  

That in some way it was there divine right to be there, they are just better designed than the plebs.  

Gault advocated the encouragement of healthy fit capable people to have more children, with the idea of improving the human gene pool. 

Gault Quote: What nature does blindly, slowly and ruthlessly, man may do providently, quickly and kindly. (10) 

Eugenics is a movement that is aimed at improving the genetic composition of the human race. Historically, eugenicists advocated selective breeding to achieve these goals. 

In modern-day science these eugenicists are still attempting to change our genetic makeup, it’s now called CRISPR (that’s for another day) 


In the Oxford dictionary epigenetics means; 

 ‘The study of changes in organisms caused by modification of gene expression rather than alteration of the genetic code itself’ 

In simple terms this means our genetics are being changed in our own lifetimes, on top of our born with genetics. These external modifications to DNA can literally turn them on or off and they alter or mutate the physical structure of our DNA. Happy days. (11

Who discovered DNA? 

DNA stands for deoxyribonucleic acid. Apparently, it was first identified in the 1860s by a Swiss chemist Johann Miescher (1). When researching white blood cells, he found a substance that had different properties he hadn’t seen before, he called this new mysterious substance ‘nuclein’ (2) because he thought it had come from the cell nucleus. Unbeknown to Johann he’d discovered DNA. 

Roll on more than 80 years before anyone else realised the magnitude these findings. The people who did were American student biologist James Watson (left) and English physicist Francis Crick (right) (3).

In 1947 after working for the Admiralty during WW2, Crick went from physics to biology (as you do), and he began to work at Cambridge University.  

By 1949, he was working at the Medical Research Council (3a) unit at the Cavendish Laboratory in Cambridge. He was joined by American student James Watson (4) and the two started to work together. Both of them discovered the ‘double helix’ which is the twisted ladder structure we’re shown that represents DNA. 

And so the Global Genetic race began. 

What is a Gene? 

I’ll let the experts give you an explanation, this excerpt is from the National Human Genome Research Institute, they should know what they’re talking about. (5)   

‘The gene is the basic physical unit of inheritance. Genes are passed from parents to offspring and contain the information needed to specify traits. Genes are arranged, one after another, on structures called chromosomes. A chromosome contains a single, long DNA molecule, only a portion of which corresponds to a single gene. Humans have approximately 20,000 genes arranged on their chromosomes’ 

What Role Does the MTHFR Gene Play? 

So, let’s get to the crux of the article. MTHFR or Methylenetetrahydrofolate reductase, let’s stick with MTHFR it’s going to be easier. (5a

Everyone inherits two copies of the MTHFR gene, one from mum, one from dad. Each copy can be normal or have a defect. As I showed epigenetics can also mutate genes, like the MTHFR.

This defect is a change in the DNA sequence that affects how much protein the gene can produce.

These defects are called mutations. The common mutation in the MTHFR gene is a single change in DNA sequence that reduces the activity of the protein produced. About 10-15% of people have both copies of the gene affected by this mutation. 

These people have very low activity of the MTHFR protein in the body. This means we have a reduced ability to convert folic acid into a usable form and can lead to accumulation of the amino acid homocysteine, which is toxic to the body. 

When we eat foods that contain folic acid, MTHFR converts it into methyl-folate (folate’s active form). Methyl-folate is critical to methylation, which helps to optimize a huge number of processes in your body including the production of DNA, metabolism of hormones, and proper detoxification. 

What Happens when the MTHFR Gene Turns Off? 

Environmental Chemicals and EMFs are playing a part in turning off and mutating genes. But what are the consequences.

The MTHFR gene mutation has been found to be one of the factors that puts people at an increased risk of; 

  • Cancer
  • cardiovascular and thromboembolic diseases (specifically blood clots, stroke, embolism, and heart attacks)
  • foetal development problems
  • depression
  • dementia
  • anxiety
  • bipolar disorder
  • schizophrenia
  • colon cancer
  • acute leukaemia
  • infertility
  • migraine
  • chronic pain and fatigue (13)

So, if it’s clear to mainstream science that the gene mutation causes these diseases, what’s the middle man?  

In a word DETOX. If our bodies are unable to detoxify, we cannot get rid of the rubbish like petrochemical residue that we all carry around inside our bodies.  

That WILL (not might) start the process of disease.  

Science has found about 20,000 human genes; they have also found 1000s of faults in these genes. Some people are lucky they have just a few, some are unlucky and have a lot. Some may have a few but they’re really bad and so on.   

Through a lifetime collecting environmental toxins in the body, those chemicals will lodge somewhere. Because of the MTHFR mutation the body will be unable to eliminate these toxins via detoxification.  

The toxins will then change our DNA mutating genes like MTHFR. That collection of toxins will then find the weak spots and go on to cause disease. 

Folic Acid and MTHFR 

The NHS recommend that you take 400mcg of Folic Acid every day, before a woman becomes pregnant. Not after, always before, a woman becomes pregnant and up until you are 12 weeks. (6) This is to reduce the risks of problems in the baby’s development in the early weeks of pregnancy. 

The problem is most people do not do this; they take it after they’re pregnant. If your mother did not or was low in dietary folic acid it may be the reason or at least one of the reasons for your current health issues. 

In the first 12 weeks the foetus is now fully formed, but there are still lots of growing taking place.  

Week 1-4 Embryo -Face, Mouth, lower jaw, throat, blood cells, circulation, heart. 

Week 5-8 Foetus – Facial features, ears, arms and legs. The neural tube (brain, spinal cord and other neural tissue of the central nervous system) is well formed now. The digestive tract and sensory organs begin to develop too. Bone starts to replace cartilage. 

Week 9-12 – baby’s arms, hands, fingers, feet and toes. Fingernails and toenails, external ears, baby’s reproductive organs also develop, circulatory and urinary systems, liver produces bile. 

These first 3 months are the critical time for development, if this pattern is interrupted by a nutritional deficiency like folic acid, then areas of development for the foetus will be interrupted. (7)

Later in life these early faults that were not noticeable in behaviour or physical performance. But, once a life is being or has been lived these defects or weak spots will be discovered by things like toxicity, infections, pressure or stress.

The ferocity of disease will be depended on the size of the fault or faults. These will also accumulate over time. Remember the EMC study, here’s a reminder. (8)

Environmental Working Group (EWG) 

In 2005 the Environmental Working Group (EWG) in the US published the results from a small study of newly born kids. It was the first time this had been done. Before this study science thought that the placenta and umbilical cord were the barrier to all chemical entry. What they found was pretty eye opening to say the least. 

The tests showed that up to 287 industrial chemicals had broken through into the unborn babies. Please keep in mind that this study only tested for a few of the 75,000 industrial chemicals used and imported into the US. Imagine if they’d tested for all 75,000. 

EWG,  The Body of Burden: The Study of Newborns

“In a study spearheaded by the Environmental Working Group (EWG), researchers at two major laboratories found an average of 200 industrial chemicals and pollutants in umbilical cord blood in babies born in August and September of 2004 in U.S. hospitals. 

Of the 287 chemicals we detected in umbilical cord blood, we know that 180 cause cancer in humans or animals, 217 are toxic to the brain and nervous system, and 208 cause birth defects or abnormal development ” 

Say no more.

Chorine can Change Your DNA 

Here is an example of an everyday thing that can alter our DNA;

For years I’ve been rattling on to friends and family and anyone who would listen, that chlorinated drinking water, and other chemicals in food, air, furniture, cleaning products and pharmaceuticals, are changing our genetic structures. Here’s a story from Duke University research blog. Full story here (12

Researchers in Spain found, based on interviews, that swimmers had a 1.6-fold increase for bladder cancer.  

Then, in 2010, DeMarini and his colleagues showed that after a 40-minute workout, swimmers’ cells created micronuclei, suggesting damage was done to the DNA so that other nuclei formed as the cell began to divide. 

Together, the teams were able to identify a specific gene that makes some individuals more susceptible to DNA damage from DPBs, further increasing their cancer risks.  

MTHFR variants are found in people worldwide. In some ethnicities, the chance to have at least one MTHFR variant is as high as 50%. Between 10%-15% of the Caucasian population and more than 25% of the Latino population have variants in both copies of the MTHFR gene. (14)

Do you remember Dolly the genetically modified sheep? Or the mouse with an ear genetically grown on its back?  

These were all experiments done in the 1990s. Imagine where this technology is now. 

This was a brief article, quite a long one. I want to get you all thinking about what is happening. There are different variants of the MTHFR mutation, and the Homocysteine, Folic Acid link are an article on their own. So is CRISPR. 

CRISPR is the next generation of vaccines.

I am not advocating genetic testing, and I’m not saying that everything we’re told about genetics from our health institutions is true, but they are pumping a lot of our money in this research.  

What I wanted to show is that there is a very strong possibility that our DNA has been or is in the process of being altered by design. I think the proof is obvious.  

It’s impossible for us as individuals to go back and see if our ancestor’s DNA was comparable with ours.  

Did they have the same mutations? If they did were the same diseases rampaging through their society? 

The answers are no, these are modern phenomena.  

We just sit back accept them and the toxic treatments provided, without doing any of our own research.

Environmental factors are unlocking our DNA and opening up our genetic weaknesses or mutating our genes in our own lifetimes. This is epigenetics. 

This leaves us open for attack, and makes us too weak to defend ourselves.